EnhanceIT Polymer Solution is a supplement for regular polyacrylamide (paa) gels for DNA/RNA separation. The chemical properties of EnhanceIT alter the characteristics of paa gels such that their resolving power is substantially increased, resulting in much shorter gels and running times. A 1 bp resolution can be achieved on 8 cm running distance; 4 bp on 4 cm!

Using shorter paa gels has several advantages: the gels are easier to prepare and handle, they allow faster runs, and shorter gels will consume less staining reagents. In addition, due to the higher resolving power of paa gels including EnhanceIT, hence the shortened running distance, the bands appear sharper and less DNA is required. Consequently, EnhanceIT gels have a higher sensitivity.

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