The GateKeepers of Innate Immunity
Innate immunity as the first line of defense

The innate immune system is an ancient host defense mechanism found in almost every multicellular organism from plants to humans. In invertebrates it is the sole mechanism of defense against pathogens but in higher vertebrates constitutes the first line of defense.

IMGENEX IHC Validated Antibodies include an expanding listing of polyclonal and monoclonal antibodies to add to our market leading product offering for Immunohistochemistry. Our IHC Validated Portfolio includes both commodity clones as well as IMGENEX original classic antibodies.

• Apoptosis: BAD, Bax,  Bcl-2, Caspases, Smac/Diablo, Survivin
• Cancer & Related Markers: β-Catenin, Cyclins, Estrogen Receptor, Myc, p53, p70, PKC, Progesterone Receptor, PTEN, STATs, VEGF
• Dendritic Cells: BDCA-2, DC-SIGN, Dectin-2, MIP3α CLEC9A
• Epigenetics: DNMT1, DNMT3a, DNMT3b
• Neurosciences: Dopamine Receptors, GPCRs, HT Receptors, GABA Receptors
• Stem Cell & development Biology: Transcription Factors, SOX2, Frizzled, KLF4, Myc
• T Cells & T Cell Subsets: Tregs and Th17 related markers, ROR_^y/ROR_^y(t), IL-23R, EBI3, Bcl-6, IL-17A, IL-17F, ZAP70
• TLRs, Innate & Adaptive immunity: TLRs, HMGB1, CD Markers, EBI3, Cytokine and Chemokine Receptors
• Inflammation: IL-17A, IL-17F, HMGB1, NALP1, NALP2, NALP4, RAGE
• Tissue Microarrays (TMAs): TMAs for specific cancers - Breast, Ovarian, Prostate, Lung and normal tissues