Novus Biologicals is een leverancier van producten voor wetenschappelijk onderzoek, waaronder antilichamen, recombinante eiwitten en siRNA. Door deze producten op grote schaal beschikbaar te maken voor zowel institutionele als commerciële onderzoekers, speelt Novus een belangrijke rol in het bevorderen van biologisch onderzoek. Al hun producten worden geleverd met gedetailleerde technische informatie en doorlopende ondersteuning. Novus richt zich met hun producten op het gebied van apoptose, autofagie, kanker, DNA reparatie, epitoop tagging, GPCR, hypoxie, lipiden en metabolisme, neurowetenschappen en stamcel markers.

Belangrijkste Productlijnen:

• Primaire Antilichamen
• Secundaire Antilichamen
• Controles
• Lysaten
• RNAi

Meer informatie kunt u vinden op: www.novusbio.com

Nodal Antibody (NBP1-71686)

NODAL is an important TGF-beta family protein in cellular differentiation. While constitutively expressed in many developing tissues, NODAL is problematically associated with the differentiation and development of many cancers. The expression of NODAL is regulated by a Notch signaling pathway, which when disrupted contributes to the aggressive behavior of metastatic cancer cells, particularly in melanoma. The abundance of NODAL expression in melanoma can help determine the stage of cancer and metastatic type/progression when tested in IHC. NODAL interactions with Cripto also predispose toward tumor progression. Overexpression of NODAL is also associated with preeclamptic placenta.

Everything you need to perform Chromatin Immunoprecipitation

Novus Biologicals’ ChromataChIP™ Kits are a complete pack to help you perform Chromatin Immunoprecipitation efficiently and accurately in your laboratory. We’ve taken all the guesswork out of ChIP by testing multiple component options to find the best possible component for you.

ChromataChIP TM Kit Components
Each kit comes with everything you need to perform ChIP, including a colorful, step-by-step manual to walk you through the 5 main phases of ChIP.

• Positive Control Antibody
• Positive Control Primers (RPL30)
• 10X Glycine
• IP Dilution Buffer
• IP Wash Buffer 1
• IP Wash Buffer 2
• IP Wash Buffer 3
• IP Wash Buffer 4
• IP Elution Buffer
• NaCl solution
• Proteinase K
• Protein A/G Magnetic Beads
• DNA Purification Kit
• Magnetic Rack