Finding the right competent cell for your application is easy with our extensive line of competent cells! We have innovatieve strains to match every cloning strategy. Our comprehensive collection of strains includes the highest transformation efficiencies available. Our specialty cells are ideal for your difficult or unusual cloning projects. Use the downloadable chart to match your application to the perfect strain.

A collection of classic strains and competent cells.

The economical competent cell packs are available to help optimize experimental design; two available formats to address both routine and difficult cloning requirements.

The XL1-Blue MRF´ Competent Cells were engineered to provide highly efficient and representational cloning of methylated DNA. These restriction-minus versions of XL1-Blue Competent Cells are deficient in all known E. coli K12 restriction systems. Use XL1-Blue MRF´ cells when cloning methylated cDNA, genomic DNA, or methylated PCR products.

Highest efficiency competent cells in convenient pacakaging designed to satisfy higher throughput requirements. For ultimate convenience we offer custom configurations, formulations, and packaging options. Visit our custom & bulk services page, or contact your local sales specialist.

These competent cells offer the highest transformation efficiencies available, enabling dramatically improved transformation efficiencies when cloning large plasmids and ligated DNA.

Electroporation-competent cells capable of producing greater than 1 × 10 10 transformants/µg of DNA. These electroporation-ready cells need only be thawed, mixed with DNA, and electroporated. TG1 electroporation-competent cells are recommended for preparation of phage display libraries.

These competent cells enable a highly efficient, rapid, and reproducible method for introducing random mutations in a cloned gene of interest. This method involves propagating the cloned gene into XL1-Red Competent Cells; an Escherichia coli strain which is deficient in three of the primary DNA repair pathways.

Reliable and versatile cloning strains developed to satisfy routine application requirements.

The ABLE C strain and the ABLE K strain help solve issues associated with toxic clones. These strains reduce the copy number of common cloning vectors by ~4- and 10-fold, enhancing the probability that a toxic clone will be propagated.

These competent cell strains are the optimal host for cloning both plasmid and lambda phage vectors. The EndA– phenotype allows preparation of high-quality plasmid DNA. The F' episome carries antibiotic resistance, eliminating the need to select on minimal media plates.

Replicating eukaryotic DNA in prokaryotic cells can be problematic. Particular eukaryotic genes may contain inverted repeats or secondary structures, such as Z-DNA, that can be rearranged or deleted by E. coli DNA repair systems. The SURE competent cells are deficient in the E. coli genes involved in the rearrangement and deletion of DNA, thus improving cloning efficiencies of DNA containing irregular structures.