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22204-53-1

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(S)-(+)-Naproxene [22204-53-1] | CDX-N0061 | Chemodex

(S)-(+)-Naproxene [22204-53-1]

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Chemical. CAS: 22204-53-1. Formula: C14H14O3. MW: 230.26. Synthetic Non-selective COX inhibitor. The IC50 values for human recombinant COX-1 and -2 are 0.6-4.8 microM and 2.0-28.4 microM, respectively. Naproxen is a potent, non-steroidal, non-selective anti-inflammatory compound that acts as a Cox (cyclooxygenase) inhibitor, and inhibits both Cox-1 and Cox-2. Research indicates that the S-naproxen is a more active form than the R-naproxen. The S-naproxen enantiomer was observed to inhibit platelet aggregation, and both enantiomers decrease production of thromboxane B2. Naproxen has been demonstrated to block Abeta fibril growth and form a complex with copper (II). - Non-selective COX inhibitor. The IC50 values for human recombinant COX-1 and -2 are 0.6-4.8 microM and 2.0-28.4 microM, respectively. Naproxen is a potent, non-steroidal, non-selective anti-inflammatory compound that acts as a Cox (cyclooxygenase) inhibitor, and inhibits both Cox-1 and Cox-2. Research indicates that the S-naproxen is a more active form than the R-naproxen. The S-naproxen enantiomer was observed to inhibit platelet aggregation, and both enantiomers decrease production of thromboxane B2. Naproxen has been demonstrated to block Abeta fibril growth and form a complex with copper (II).

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