4-1BBL / CD137L antibody [N2C3]

Catalog number: GTX117355_25ul
Brand: GeneTex
Packing: 25 ul
Other sizes: 100 ul
Price: € 172.00
Expected delivery time: 10 days
Quantity:

Product specifications for - 4-1BBL / CD137L antibody [N2C3]

Overview: 
Product group: Antibodies
Category: Primary Antibodies
Application: ImmunoPrecipitation; Western Blot
Species: Human
Host: Rabbit
Target: TNFSF9
Target description: TNF superfamily member 9
Clonality: Polyclonal
Conjugation: Unconjugated
Isotype: IgG
Controle: A549 , HeLa , HepG2 , HCT116
Properties: 
Datasheet: Datasheet
  Research Use Only
UNSPSC: 12352203
Concentration: 1 mg/ml
Storage instructions: 2-¦C to 8-¦C, -20-¦C or -80-¦C
Scientific information: 
Scientific info: The protein encoded by this gene is a cytokine that belongs to the tumor necrosis factor (TNF) ligand family. This transmembrane cytokine is a bidirectional signal transducer that acts as a ligand for TNFRSF9/4-1BB, which is a costimulatory receptor molecule in T lymphocytes. This cytokine and its receptor are involved in the antigen presentation process and in the generation of cytotoxic T cells. The receptor TNFRSF9/4-1BB is absent from resting T lymphocytes but rapidly expressed upon antigenic stimulation. The ligand encoded by this gene, TNFSF9/4-1BBL, has been shown to reactivate anergic T lymphocytes in addition to promoting T lymphocyte proliferation. This cytokine has also been shown to be required for the optimal CD8 responses in CD8 T cells. This cytokine is expressed in carcinoma cell lines, and is thought to be involved in T cell-tumor cell interaction.
Gene ID: 8744
Swiss prot ID: P41273
Additional information: 
Synonyms: 4-1BB ligand; 4-1BBL; 4-1BB-L; CD137L; homolog of mouse 4-1BB-L; receptor 4-1BB ligand; TNLG5A; tumor necrosis factor (ligand) superfamily, member 9; tumor necrosis factor ligand 5A; tumor necrosis factor ligand superfamily member 9; tumor necrosis factor superfamily member 9