5-Hydroxymethylcytosine / 5-hmC antibody [GT13612]

Melatonin impedes Tet1-dependent mGluR5 promoter demethylation to relieve pain. Hsieh MC et al., 2017 Nov, J Pineal Res

Restoration of TET2 deficiency inhibits tumor growth in head neck squamous cell carcinoma. Huang R et al., 2020 Mar, Ann Transl Med

SIRT1 Activation Disrupts Maintenance of Myelodysplastic Syndrome Stem and Progenitor Cells by Restoring TET2 Function. Sun J et al., 2018 Sep 6, Cell Stem Cell

Tet1-dependent epigenetic modification of BDNF expression in dorsal horn neurons mediates neuropathic pain in rats. Hsieh MC et al., 2016 Nov 18, Sci Rep

TET1-mediated DNA hydroxymethylation activates inhibitors of the Wnt/beta-catenin signaling pathway to suppress EMT in pancreatic tumor cells. Wu J et al., 2019 Aug 9, J Exp Clin Cancer Res

TP53 inactivation and expression of methylation-associated proteins in gastric adenocarcinoma with enteroblastic differentiation. Yatagai N et al., 2019 Mar, Virchows Arch