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GTX101395 IHC-P Image
GTX101395 IHC-P Image
GTX101395 IHC-P Image

ACE2 antibody [N1N2], N-term

Research Use Only
GTX101395
GeneTex
Product group Antibodies
Price on request
Packing Size
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Overview

  • Supplier
    GeneTex
  • Product Name
    ACE2 antibody [N1N2], N-term
  • Delivery Days Customer
    9
  • Certification
    Research Use Only
  • Concentration
    0.2 mg/ml
  • Isotype
    IgG
  • Scientific Description
    The protein encoded by this gene belongs to the angiotensin-converting enzyme family of dipeptidyl carboxydipeptidases and has considerable homology to human angiotensin 1 converting enzyme. This secreted protein catalyzes the cleavage of angiotensin I into angiotensin 1-9, and angiotensin II into the vasodilator angiotensin 1-7. The organ- and cell-specific expression of this gene suggests that it may play a role in the regulation of cardiovascular and renal function, as well as fertility. In addition, the encoded protein is a functional receptor for the spike glycoprotein of the human coronaviruses SARS and HCoV-NL63. [provided by RefSeq]
  • Storage Instruction
    2°C to 8°C,-20°C
  • UNSPSC
    12352203

References

  • A comparative analysis of SARS-CoV-2 antivirals characterizes 3CLpro inhibitor PF-00835231 as a potential new treatment for COVID-19. de Vries M et al., 2021 Feb 23, J Virol
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  • A comparative analysis of SARS-CoV-2 antivirals in human airway models characterizes 3CLpro inhibitor PF-00835231 as a potential new treatment for COVID-19. de Vries M et al., 2021 Feb 19, bioRxiv
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  • Antiglaucomatous effects of the activation of intrinsic Angiotensin-converting enzyme 2. Foureaux G et al., 2013 Jun 21, Invest Ophthalmol Vis Sci
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  • Effects of Basic Amino Acids and Their Derivatives on SARS-CoV-2 and Influenza-A Virus Infection. Melano I et al., 2021 Jul 4, Viruses
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  • Hesperidin Is a Potential Inhibitor against SARS-CoV-2 Infection. Cheng FJ et al., 2021 Aug 16, Nutrients
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  • Restricted Water Intake and Hydration with Fructose-Containing Beverages during Infancy Predispose to Aggravate an Acute Renal Ischemic Insult in Adolescent Rats. Garcia-Arroyo FE et al., 2020, Biomed Res Int
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  • RIG-I triggers a signaling-abortive anti-SARS-CoV-2 defense in human lung cells. Yamada T et al., 2021 Jul, Nat Immunol
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  • Stimulation of the ACE2/Ang-(1-7)/Mas axis in hypertensive pregnant rats attenuates cardiovascular dysfunction in adult male offspring. Bessa ASM et al., 2019 Dec, Hypertens Res
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  • The angiotensin converting enzyme 2/angiotensin-(1-7)/Mas Receptor axis as a key player in alveolar bone remodeling. Queiroz-Junior CM et al., 2019 Nov, Bone
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  • Whartons Jelly Mesenchymal Stem Cell-Derived Extracellular Vesicles Reduce SARS-CoV2-Induced Inflammatory Cytokines Under High Glucose and Uremic Toxin Conditions. Khanh VC et al., 2021 Aug 1, Stem Cells Dev
    Read more