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GTX105495 ICC/IF Image
GTX105495 ICC/IF Image
GTX105495 ICC/IF Image

AChR alpha 3 antibody

Research Use Only
GTX105495
GeneTex
Product group Antibodies
Price on request
Packing Size
Large volume orders?
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Overview

  • Supplier
    GeneTex
  • Product Name
    AChR alpha 3 antibody
  • Delivery Days Customer
    9
  • Certification
    Research Use Only
  • Concentration
    1 mg/ml
  • Isotype
    IgG
  • Scientific Description
    This locus encodes a member of the nicotinic acetylcholine receptor family of proteins. Members of this family of proteins form pentameric complexes comprised of both alpha and beta subunits. This locus encodes an alpha-type subunit, as it contains characteristic adjacent cysteine residues. The encoded protein is a ligand-gated ion channel that likely plays a role in neurotransmission. Polymorphisms in this gene have been associated with an increased risk of smoking initiation and an increased susceptibility to lung cancer. Alternatively spliced transcript variants have been described. [provided by RefSeq]
  • Storage Instruction
    2°C to 8°C,-20°C
  • UNSPSC
    12352203

References

  • The expression of the nicotinic acetylcholine receptor alpha3 subunit in the brains of patients with Alzheimers disease and its effects on alpha- and gamma-secretases and Notch signal transduction in SH-SY5Y cells. Ren J et al., 2019, Int J Clin Exp Pathol
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