ACK1 antibody

GeneTex

ACK1 antibody

10

ImmunoPrecipitation, Western Blot, ELISA

Research Use Only

Polyclonal

0.59-0.68 mg/ml

Rabbit

IgG

This gene encodes a tyrosine kinase that binds Cdc42Hs in its GTP-bound form and inhibits both the intrinsic and GTPase-activating protein (GAP)-stimulated GTPase activity of Cdc42Hs. This binding is mediated by a unique sequence of 47 amino acids C-terminal to an SH3 domain. The protein may be involved in a regulatory mechanism that sustains the GTP-bound active form of Cdc42Hs and which is directly linked to a tyrosine phosphorylation signal transduction pathway. Several alternatively spliced transcript variants have been identified from this gene, but the full-length nature of only two transcript variants has been determined. [provided by RefSeq, Jul 2008]

Human, Mouse, Rat

2°C to 8°C,-20°C

12352203