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GTX114237 ICC/IF Image
GTX114237 ICC/IF Image
GTX114237 ICC/IF Image

ADAR2 antibody

Research Use Only
GTX114237
GeneTex
Product group Antibodies
Price on request
Packing Size
Large volume orders?
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Overview

  • Supplier
    GeneTex
  • Product Name
    ADAR2 antibody
  • Delivery Days Customer
    9
  • Certification
    Research Use Only
  • Concentration
    1 mg/ml
  • Isotype
    IgG
  • Scientific Description
    This gene encodes the enzyme responsible for pre-mRNA editing of the glutamate receptor subunit B by site-specific deamination of adenosines. Studies in rat found that this enzyme acted on its own pre-mRNA molecules to convert an AA dinucleotide to an AI dinucleotide which resulted in a new splice site. Alternative splicing of this gene results in several transcript variants, some of which have been characterized by the presence or absence of an ALU cassette insert and a short or long C-terminal region. [provided by RefSeq]
  • Storage Instruction
    2°C to 8°C,-20°C
  • UNSPSC
    12352203

References

  • Reduced adenosine-to-inosine miR-455-5p editing promotes melanoma growth and metastasis. Shoshan E et al., 2015 Mar, Nat Cell Biol
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  • Systematic characterization of A-to-I RNA editing hotspots in microRNAs across human cancers. Wang Y et al., 2017 Jul, Genome Res
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  • Unbiased Identification of trans Regulators of ADAR and A-to-I RNA Editing. Freund EC et al., 2020 May 19, Cell Rep
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