GTX113381 WB Image
GTX113381 WB Image
AKR1B1 antibody [N1C3]
GTX113381
Product group Antibodies
Overview
- SupplierGeneTex
- Product NameAKR1B1 antibody [N1C3]
- Delivery Days Customer9
- CertificationResearch Use Only
- Concentration1.06 mg/ml
- IsotypeIgG
- Scientific DescriptionThis gene encodes a member of the aldo/keto reductase superfamily, which consists of more than 40 known enzymes and proteins. This member catalyzes the reduction of a number of aldehydes, including the aldehyde form of glucose, and is thereby implicated in the development of diabetic complications by catalyzing the reduction of glucose to sorbitol. Multiple pseudogenes have been identified for this gene. The nomenclature system used by the HUGO Gene Nomenclature Committee to define human aldo-keto reductase family members is known to differ from that used by the Mouse Genome Informatics database. [provided by RefSeq]
- Storage Instruction2°C to 8°C,-20°C
- UNSPSC12352203
References
- 3H-1,2-Dithiole-3-Thione Protects Lens Epithelial Cells against Fructose-Induced Epithelial-Mesenchymal Transition via Activation of AMPK to Eliminate AKR1B1-Induced Oxidative Stress in Diabetes Mellitus. Wu TT et al., 2021 Jul 6, Antioxidants (Basel)Read more
- A Role for Both V1a and V2 Receptors in Renal Heat Stress Injury Amplified by Rehydration with Fructose. Garcia-Arroyo FE et al., 2019 Nov 16, Int J Mol SciRead more
- AKR1B1-Induced Epithelial-Mesenchymal Transition Mediated by RAGE-Oxidative Stress in Diabetic Cataract Lens. Wu TT et al., 2020 Mar 25, Antioxidants (Basel)Read more
- Dicarbonyl stress and glyoxalase enzyme system regulation in human skeletal muscle. Mey JT et al., 2018 Feb 1, Am J Physiol Regul Integr Comp PhysiolRead more
- Fructose Synthesis and Transport at the Uterine-Placental Interface of Pigs: Cell-Specific Localization of SLC2A5, SLC2A8, and Components of the Polyol Pathway. Steinhauser CB et al., 2016 Nov, Biol ReprodRead more
- Rehydration with soft drink-like beverages exacerbates dehydration and worsens dehydration-associated renal injury. Garcia-Arroyo FE et al., 2016 Jul 1, Am J Physiol Regul Integr Comp PhysiolRead more
- Sorbitol dehydrogenase overexpression and other aspects of dysregulated protein expression in human precancerous colorectal neoplasms: a quantitative proteomics study. Uzozie A et al., 2014 May, Mol Cell ProteomicsRead more
- Targeting NPL4 via drug repositioning using disulfiram for the treatment of clear cell renal cell carcinoma. Yoshino H et al., 2020, PLoS OneRead more