GTX123973 ICC/IF Image
GTX123973 ICC/IF Image
ALDH1A1 antibody
GTX123973
Product group Antibodies
Overview
- SupplierGeneTex
- Product NameALDH1A1 antibody
- Delivery Days Customer9
- CertificationResearch Use Only
- Concentration1 mg/ml
- IsotypeIgG
- Scientific DescriptionThis protein belongs to the aldehyde dehydrogenases family of proteins. Aldehyde dehydrogenase is the second enzyme of the major oxidative pathway of alcohol metabolism. Two major liver isoforms of this enzyme, cytosolic and mitochondrial, can be distinguished by their electrophoretic mobilities, kinetic properties, and subcellular localizations. Most Caucasians have two major isozymes, while approximately 50% of Orientals have only the cytosolic isozyme, missing the mitochondrial isozyme. A remarkably higher frequency of acute alcohol intoxication among Orientals than among Caucasians could be related to the absence of the mitochondrial isozyme. This gene encodes a cytosolic isoform, which has a high affinity for aldehydes. [provided by RefSeq]
- Storage Instruction2°C to 8°C,-20°C
- UNSPSC12352203
References
- 6-(Methylsulfinyl)hexyl isothiocyanate protects acetaldehyde-caused cytotoxicity through the induction of aldehyde dehydrogenase in hepatocytes. Kitakaze T et al., 2020 Jun 15, Arch Biochem BiophysRead more
- A potent indolylquinoline alleviates growth of human lung cancer cell tumorspheres. Ni YL et al., 2017 Oct, ApoptosisRead more
- ALDH1A1 Inhibits Chicken Preadipocytes Proliferation and Differentiation via the PPARgamma Pathway In Vitro and In Vivo. Zhang J et al., 2020 Apr 29, Int J Mol SciRead more
- Antifibrotic effect of lung-resident progenitor cells with high aldehyde dehydrogenase activity. Takahashi H et al., 2021 Aug 23, Stem Cell Res TherRead more
- Cell Type- and Sex-Dependent Transcriptome Profiles of Rat Anterior Pituitary Cells. Fletcher PA et al., 2019, Front Endocrinol (Lausanne)Read more
- Expression and associations of TRAF1, BMI-1, ALDH1, and Lin28B in oral squamous cell carcinoma. Wu TF et al., 2017 Apr, Tumour BiolRead more
- GATA6 enhances the stemness of human colon cancer cells by creating a metabolic symbiosis through upregulating LRH-1 expression. Lai HT et al., 2020 Jun, Mol OncolRead more
- Identification of thiostrepton as a novel therapeutic agent that targets human colon cancer stem cells. Ju SY et al., 2015 Jul 2, Cell Death DisRead more
- MiR-21-5p Links Epithelial-Mesenchymal Transition Phenotype with Stem-Like Cell Signatures via AKT Signaling in Keloid Keratinocytes. Yan L et al., 2016 Sep 6, Sci RepRead more
- NLRP3 inflammasome activation promotes inflammation-induced carcinogenesis in head and neck squamous cell carcinoma. Huang CF et al., 2017 Sep 2, J Exp Clin Cancer ResRead more