GTX101429 ELISA Image
GTX101429 ELISA Image
ALDH2 antibody
GTX101429
Product group Antibodies
Overview
- SupplierGeneTex
- Product NameALDH2 antibody
- Delivery Days Customer9
- CertificationResearch Use Only
- Concentration0.23 mg/ml
- IsotypeIgG
- Scientific DescriptionThis protein belongs to the aldehyde dehydrogenase family of proteins. Aldehyde dehydrogenase is the second enzyme of the major oxidative pathway of alcohol metabolism. Two major liver isoforms of this enzyme, cytosolic and mitochondrial, can be distinguished by their electrophoretic mobilities, kinetic properties, and subcellular localizations. Most Caucasians have two major isozymes, while approximately 50% of Orientals have only the cytosolic isozyme, missing the mitochondrial isozyme. A remarkably higher frequency of acute alcohol intoxication among Orientals than among Caucasians could be related to the absence of the mitochondrial isozyme. This gene encodes a mitochondrial isoform, which has a low Km for acetaldehydes, and is localized in mitochondrial matrix. [provided by RefSeq]
- Storage Instruction2°C to 8°C,-20°C
- UNSPSC12352203
References
- 6-(Methylsulfinyl)hexyl isothiocyanate protects acetaldehyde-caused cytotoxicity through the induction of aldehyde dehydrogenase in hepatocytes. Kitakaze T et al., 2020 Jun 15, Arch Biochem BiophysRead more
- Proteomics of muscle chronological ageing in post-menopausal women. Gueugneau M et al., 2014 Dec 23, BMC GenomicsRead more
- beta-catenin is essential for ethanol metabolism and protection against alcohol-mediated liver steatosis in mice. Liu S et al., 2012 Mar, HepatologyRead more