GTX113115 WB Image
alpha Actinin 4 antibody [N2C1], Internal
GTX113115
Product group Antibodies
Overview
- SupplierGeneTex
- Product Namealpha Actinin 4 antibody [N2C1], Internal
- Delivery Days Customer9
- CertificationResearch Use Only
- Concentration1.03 mg/ml
- IsotypeIgG
- Scientific DescriptionAlpha actinins belong to the spectrin gene superfamily which represents a diverse group of cytoskeletal proteins, including the alpha and beta spectrins and dystrophins. Alpha actinin is an actin-binding protein with multiple roles in different cell types. In nonmuscle cells, the cytoskeletal isoform is found along microfilament bundles and adherens-type junctions, where it is involved in binding actin to the membrane. In contrast, skeletal, cardiac, and smooth muscle isoforms are localized to the Z-disc and analogous dense bodies, where they help anchor the myofibrillar actin filaments. This gene encodes a nonmuscle, alpha actinin isoform which is concentrated in the cytoplasm, and thought to be involved in metastatic processes. Mutations in this gene have been associated with focal and segmental glomerulosclerosis. [provided by RefSeq]
- Storage Instruction2°C to 8°C,-20°C
- UNSPSC12352203