Overview
- SupplierGeneTex
- Product Namealpha Tubulin 1A antibody
- Delivery Days Customer9
- CertificationResearch Use Only
- Concentration0.73 mg/ml
- IsotypeIgG
- Scientific DescriptionMicrotubules of the eukaryotic cytoskeleton perform essential and diverse functions and are composed of a heterodimer of alpha and beta tubulins. The genes encoding these microtubule constituents belong to the tubulin superfamily, which is composed of six distinct families. Genes from the alpha, beta and gamma tubulin families are found in all eukaryotes. The alpha and beta tubulins represent the major components of microtubules, while gamma tubulin plays a critical role in the nucleation of microtubule assembly. There are multiple alpha and beta tubulin genes, which are highly conserved among species. This gene encodes alpha tubulin and is highly similar to mouse and rat Tuba1 gene. Northern blotting studies have shown that the gene expression is predominantly found in morphologically differentiated neurologic cells. This gene is one of three alpha-tubulin genes in a cluster on chromosome 12q. [provided by RefSeq]
- Storage Instruction2°C to 8°C,-20°C
- UNSPSC12352203
References
- Aryl hydrocarbon receptor in association with RelA modulates IL-6 expression in non-smoking lung cancer. Chen PH et al., 2012 May 17, OncogeneRead more
- Role of estrogen receptors and Src signaling in mechanisms of bone metastasis by estrogen receptor positive breast cancers. Chiu JH et al., 2017 May 4, J Transl MedRead more
- Translocation of Helicobacter pylori CagA into Human B lymphocytes, the origin of mucosa-associated lymphoid tissue lymphoma. Lin WC et al., 2010 Jul 15, Cancer ResRead more