AMACR / p504S Antibody (Prostate Cancer Marker)
ORB385979
Overview
- SupplierBiorbyt
- Product NameAMACR / p504S Antibody (Prostate Cancer Marker)
- Delivery Days Customer16
- ApplicationsImmunoHistoChemistry
- Applications SupplierWestern blot: 0.5-2ug/ml,Immunohistochemistry (FFPE): 1-2ug/ml for 30 min at RT IHC-P, WB
- CertificationResearch Use Only
- Clone IDAMACR/1723
- Scientific DescriptionAMACR, also known as p504S is an enzyme that is involved in bile acid biosynthesis and beta-oxidation of branched-chain fatty acids. It is expressed in cells of premalignant high-grade prostatic intraepithelial neoplasia (HGPIN) and prostate adenocarcinoma. The majority of the carcinoma cells show a distinct granular cytoplasmic staining reaction. AMACR is present at low or undetectable levels in glandular epithelial cells of normal prostate and benign prostatic hyperplasia. A spotty granular cytoplasmic staining is seen in a few cells of the benign glands.
- UNSPSC12352203