Bio-Connect

AMACR / p504S Antibody (Prostate Cancer Marker)

Research Use Only
ORB385979
Biorbyt
ApplicationsImmunoHistoChemistry
Product group Antibodies
Price on request
Packing Size
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Overview

  • Supplier
    Biorbyt
  • Product Name
    AMACR / p504S Antibody (Prostate Cancer Marker)
  • Delivery Days Customer
    16
  • Applications
    ImmunoHistoChemistry
  • Applications Supplier
    Western blot: 0.5-2ug/ml,Immunohistochemistry (FFPE): 1-2ug/ml for 30 min at RT IHC-P, WB
  • Certification
    Research Use Only
  • Clone ID
    AMACR/1723
  • Scientific Description
    AMACR, also known as p504S is an enzyme that is involved in bile acid biosynthesis and beta-oxidation of branched-chain fatty acids. It is expressed in cells of premalignant high-grade prostatic intraepithelial neoplasia (HGPIN) and prostate adenocarcinoma. The majority of the carcinoma cells show a distinct granular cytoplasmic staining reaction. AMACR is present at low or undetectable levels in glandular epithelial cells of normal prostate and benign prostatic hyperplasia. A spotty granular cytoplasmic staining is seen in a few cells of the benign glands.
  • UNSPSC
    12352203