GTX110348 IHC-P Image
GTX110348 IHC-P Image
Aminoacylase 1 antibody [N2C3-2]
GTX110348
Product group Antibodies
Overview
- SupplierGeneTex
- Product NameAminoacylase 1 antibody [N2C3-2]
- Delivery Days Customer9
- CertificationResearch Use Only
- Concentration1 mg/ml
- IsotypeIgG
- Scientific DescriptionAminoacylase-1 is a cytosolic, homodimeric, zinc-binding enzyme that catalyzes the hydrolysis of acylated L-amino acids to L-amino acids and acyl group, and has been postulated to function in the catabolism and salvage of acylated amino acids. ACY1 has been assigned to chromosome 3p21.1, a region reduced to homozygosity in small-cell lung cancer (SCLC), and its expression has been reported to be reduced or undetectable in SCLC cell lines and tumors. The amino acid sequence of human aminoacylase-1 is highly homologous to the porcine counterpart, and ACY1 is the first member of a new family of zinc-binding enzymes. [provided by RefSeq]
- Storage Instruction2°C to 8°C,-20°C
- UNSPSC12352203
References
- Expanding the phenotype in aminoacylase 1 (ACY1) deficiency: characterization of the molecular defect in a 63-year-old woman with generalized dystonia. Sass JO et al., 2016 Jun, Metab Brain DisRead more
- The molecular basis of aminoacylase 1 deficiency. Sommer A et al., 2011 Jun, Biochim Biophys ActaRead more