GTX130429 WB Image
GTX130429 WB Image
AMPK alpha 1 (phospho Thr183) + AMPK alpha 2 (phospho Thr172) antibody
GTX130429
Product group Antibodies
Overview
- SupplierGeneTex
- Product NameAMPK alpha 1 (phospho Thr183) + AMPK alpha 2 (phospho Thr172) antibody
- Delivery Days Customer9
- CertificationResearch Use Only
- Concentration2.28 mg/ml
- IsotypeIgG
- Scientific DescriptionThe protein encoded by this gene belongs to the ser/thr protein kinase family. It is the catalytic subunit of the 5-prime-AMP-activated protein kinase (AMPK). AMPK is a cellular energy sensor conserved in all eukaryotic cells. The kinase activity of AMPK is activated by the stimuli that increase the cellular AMP/ATP ratio. AMPK regulates the activities of a number of key metabolic enzymes through phosphorylation. It protects cells from stresses that cause ATP depletion by switching off ATP-consuming biosynthetic pathways. Alternatively spliced transcript variants encoding distinct isoforms have been observed. [provided by RefSeq]
- Storage Instruction2°C to 8°C,-20°C
- UNSPSC12352203
References
- Sanghuangporus sanghuang Mycelium Prevents Paracetamol-Induced Hepatotoxicity through Regulating the MAPK/NF-kappaB, Keap1/Nrf2/HO-1, TLR4/PI3K/Akt, and CaMKKbeta/LKB1/AMPK Pathways and Suppressing Oxidative Stress and Inflammation. Jiang WP et al., 2021 Jun 2, Antioxidants (Basel)Read more
- Cannabinoid receptor 1 knockout alleviates hepatic steatosis by downregulating perilipin 2. Irungbam K et al., 2020 Mar, Lab InvestRead more
- Metformin-induced AMPK activation stimulates remyelination through induction of neurotrophic factors, downregulation of NogoA and recruitment of Olig2+ precursor cells in the cuprizone murine model of multiple sclerosis. Houshmand F et al., 2019 Dec, DaruRead more
- Oleanolic Acid Inhibits Liver X Receptor Alpha and Pregnane X Receptor to Attenuate Ligand-Induced Lipogenesis. Lin YN et al., 2018 Oct 24, J Agric Food ChemRead more