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GTX103250 WB Image
GTX103250 WB Image
GTX103250 WB Image

Annexin V antibody

Research Use Only
GTX103250
GeneTex
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Product group Antibodies
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Overview

  • Supplier
    GeneTex
  • Product Name
    Annexin V antibody
  • Delivery Days Customer
    9
  • Certification
    Research Use Only
  • Concentration
    1 mg/ml
  • Isotype
    IgG
  • Scientific Description
    The protein encoded by this gene belongs to the annexin family of calcium-dependent phospholipid binding proteins some of which have been implicated in membrane-related events along exocytotic and endocytotic pathways. Annexin 5 is a phospholipase A2 and protein kinase C inhibitory protein with calcium channel activity and a potential role in cellular signal transduction, inflammation, growth and differentiation. Annexin 5 has also been described as placental anticoagulant protein I, vascular anticoagulant-alpha, endonexin II, lipocortin V, placental protein 4 and anchorin CII. The gene spans 29 kb containing 13 exons, and encodes a single transcript of approximately 1.6 kb and a protein product with a molecular weight of about 35 kDa. [provided by RefSeq]
  • Storage Instruction
    2°C to 8°C,-20°C
  • UNSPSC
    12352203

References

  • Diurnal, localized exposure of phosphatidylserine by rod outer segment tips in wild-type but not Itgb5-/- or Mfge8-/- mouse retina. Ruggiero L et al., 2012 May 22, Proc Natl Acad Sci U S A
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  • High glucose-induced proteome alterations in hepatocytes and its possible relevance to diabetic liver disease. Chen JY et al., 2013 Nov, J Nutr Biochem
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  • Identification of up- and down-regulated proteins in doxorubicin-resistant uterine cancer cells: reticulocalbin-1 plays a key role in the development of doxorubicin-associated resistance. May EW et al., 2014 Dec, Pharmacol Res
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  • The Neuroprotective Role of MiR-124-3p in a 6-Hydroxydopamine-Induced Cell Model of Parkinsons Disease via the Regulation of ANAX5. Dong RF et al., 2018 Jan, J Cell Biochem
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  • Therapeutic Challenge with a CDK 4/6 Inhibitor Induces an RB-Dependent SMAC-Mediated Apoptotic Response in Non-Small Cell Lung Cancer. Thangavel C et al., 2018 Mar 15, Clin Cancer Res
    Read more