anti-4E-BP1 antibody
ARG65800
ApplicationsImmunoFluorescence, Western Blot, ImmunoCytoChemistry, ImmunoHistoChemistry, ImmunoHistoChemistry Paraffin
Product group Antibodies
ReactivityBovine, Human, Porcine, Zebra Fish
TargetEIF4EBP1
Overview
- SupplierArigo Biolaboratories
- Product Nameanti-4E-BP1 antibody
- Delivery Days Customer23
- ApplicationsImmunoFluorescence, Western Blot, ImmunoCytoChemistry, ImmunoHistoChemistry, ImmunoHistoChemistry Paraffin
- CertificationResearch Use Only
- ClonalityPolyclonal
- ConjugateUnconjugated
- Gene ID1978
- Target nameEIF4EBP1
- Target descriptioneukaryotic translation initiation factor 4E binding protein 1
- Target synonyms4EBP1; 4E-BP1; BP-1; eIF4E-binding protein 1; eukaryotic translation initiation factor 4E-binding protein 1; PHAS-I; phosphorylated heat- and acid-stable protein regulated by insulin 1
- HostRabbit
- IsotypeIgG
- Scientific DescriptionThis gene encodes one member of a family of translation repressor proteins. The protein directly interacts with eukaryotic translation initiation factor 4E (eIF4E), which is a limiting component of the multisubunit complex that recruits 40S ribosomal subunits to the 5 end of mRNAs. Interaction of this protein with eIF4E inhibits complex assembly and represses translation. This protein is phosphorylated in response to various signals including UV irradiation and insulin signaling, resulting in its dissociation from eIF4E and activation of mRNA translation. [provided by RefSeq, Jul 2008]
- ReactivityBovine, Human, Porcine, Zebra Fish
- Storage Instruction-20°C
- UNSPSC12352203