anti-AGPS antibody [AGPS-03]

Arigo Biolaboratories

anti-AGPS antibody [AGPS-03]

23

Flow Cytometry, Western Blot

Research Use Only

Monoclonal

AGPS-03

1 mg/ml

Unconjugated

>95%

AGPS

alkylglycerone phosphate synthase

ADAP-S; ADAS; ADHAPS; ADPS; aging-associated gene 5 protein; aging-associated protein 5; ALDHPSY; alkyl-DHAP synthase; alkyldihydroxyacetonephosphate synthase, peroxisomal; RCDP3

Mouse

IgG2a

AGPS (alkylglycerone phosphate synthase), is an enzyme that catalyzes the second step of ether lipid biosynthesis in which acyl-dihydroxyacetone phosphate (acyl-DHAP) is converted to alkyl-DHAP by addition of a long chain alcohol and removal of a long-chain acid anion. The protein is localized to the inner side of the peroxisomal membrane and requires FAD as a cofactor. Mutations in AGPS gene have been associated with type 3 of rhizomelic chondrodysplasia punctata (RCDP3), and Zellweger syndrome. Higher expression of AGPS was observed in BCR/ABL positive leukemias and it was also described to be associated with higher risk of relapse.

Human

-20°C

12352203