Bio-Connect

anti-alpha Actinin 4 antibody

Research Use Only
ARG55162
Arigo Biolaboratories
ApplicationsWestern Blot
Product group Antibodies
ReactivityBovine, Chicken, Human, Mouse, Rat
TargetACTN4
Price on request
Packing Size
Large volume orders?
Order with a bulk request

Overview

  • Supplier
    Arigo Biolaboratories
  • Product Name
    anti-alpha Actinin 4 antibody
  • Delivery Days Customer
    23
  • Applications
    Western Blot
  • Certification
    Research Use Only
  • Clonality
    Polyclonal
  • Conjugate
    Unconjugated
  • Gene ID81
  • Target name
    ACTN4
  • Target description
    actinin alpha 4
  • Target synonyms
    ACTININ-4; alpha-actinin-4; focal segmental glomerulosclerosis 1; FSGS; FSGS1; non-muscle alpha-actinin 4
  • Host
    Rabbit
  • Isotype
    IgG
  • Scientific Description
    Alpha actinins belong to the spectrin gene superfamily which represents a diverse group of cytoskeletal proteins, including the alpha and beta spectrins and dystrophins. Alpha actinin is an actin-binding protein with multiple roles in different cell types. In nonmuscle cells, the cytoskeletal isoform is found along microfilament bundles and adherens-type junctions, where it is involved in binding actin to the membrane. In contrast, skeletal, cardiac, and smooth muscle isoforms are localized to the Z-disc and analogous dense bodies, where they help anchor the myofibrillar actin filaments. This gene encodes a nonmuscle, alpha actinin isoform which is concentrated in the cytoplasm, and thought to be involved in metastatic processes. Mutations in this gene have been associated with focal and segmental glomerulosclerosis. [provided by RefSeq, Jul 2008]
  • Reactivity
    Bovine, Chicken, Human, Mouse, Rat
  • Storage Instruction
    -20°C
  • UNSPSC
    12352203