anti-Amyloid Precursor Protein phospho (Thr668) antibody
ARG51685
ApplicationsWestern Blot
Product group Antibodies
ReactivityHuman
TargetAPP
Overview
- SupplierArigo Biolaboratories
- Product Nameanti-Amyloid Precursor Protein phospho (Thr668) antibody
- Delivery Days Customer23
- ApplicationsWestern Blot
- CertificationResearch Use Only
- ClonalityPolyclonal
- Concentration1 mg/ml
- ConjugateUnconjugated
- Gene ID351
- Target nameAPP
- Target descriptionamyloid beta precursor protein
- Target synonymsAAA; ABETA; ABPP; AD1; alpha-sAPP; alzheimer disease amyloid protein; amyloid beta (A4) precursor protein; amyloid beta A4 protein; amyloid precursor protein; amyloid-beta precursor protein; APPI; beta-amyloid peptide; beta-amyloid peptide(1-40); beta-amyloid peptide(1-42); beta-amyloid precursor protein; cerebral vascular amyloid peptide; CTFgamma; CVAP; peptidase nexin-II; PN2; PN-II; preA4; protease nexin-II; testicular tissue protein Li 2
- HostRabbit
- IsotypeIgG
- Modification TypePhosphorylated
- Scientific DescriptionAPP encodes a cell surface receptor and transmembrane precursor protein that is cleaved by secretases to form a number of peptides. Some of these peptides are secreted and can bind to the acetyltransferase complex APBB1/TIP60 to promote transcriptional activation, while others form the protein basis of the amyloid plaques found in the brains of patients with Alzheimer disease. Mutations in this gene have been implicated in autosomal dominant Alzheimer disease and cerebroarterial amyloidosis (cerebral amyloid angiopathy). Multiple transcript variants encoding several different isoforms have been found for this gene.
- ReactivityHuman
- Storage Instruction-20°C
- UNSPSC12352203