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anti-APRIL (mouse), mAb (rec.) (blocking) (Apry-1-3)

Research Use Only
AG-27B-0017
AdipoGen Life Sciences
ApplicationsImmunoPrecipitation, ELISA, Neutralisation/Blocking
Product group Antibodies
ReactivityMouse
TargetTnfsf13
Price on request
Packing Size
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Overview

  • Supplier
    AdipoGen Life Sciences
  • Product Name
    anti-APRIL (mouse), mAb (rec.) (blocking) (Apry-1-3)
  • Delivery Days Customer
    10
  • Applications
    ImmunoPrecipitation, ELISA, Neutralisation/Blocking
  • Certification
    Research Use Only
  • Clonality
    Monoclonal
  • Clone ID
    Apry-1-3
  • Concentration
    1 mg/ml
  • Estimated Purity
    >95%
  • Gene ID69583
  • Target name
    Tnfsf13
  • Target description
    tumor necrosis factor (ligand) superfamily, member 13
  • Target synonyms
    2310026N09Rik; a proliferation-inducing ligand; April; TA; Tall2; Tnlg7b; TRD; Trdl1; tumor necrosis factor ligand 7b; tumor necrosis factor ligand superfamily member 13
  • Host
    Human
  • Isotype
    IgG1
  • Scientific Description
    APRIL is a cytokine that belongs to the TNF superfamily and binds to TACI and BCMA. It is implicated in the regulation of tumor cell growth and is involved in monocyte/macrophage-mediated immunological processes. Anti-APRIL (mouse) Monoclonal Antibody (recombinant) (Blocking) (APRY-1-3) is an antibody developed by antibody phage display technology using a human naive antibody gene library. These libraries consist of scFv (single chain fragment variable) composed of VH (variable domain of the human immunoglobulin heavy chain) and VL (variable domain of the human immunoglobulin light chain) connected by a polypeptide linker. The antibody fragments are displayed on the surface of filamentous bacteriophage (M13). This scFv was selected by affinity selection on antigen in a process termed panning. Multiple rounds of panning are performed to enrich for antigen-specific scFv-phage. Monoclonal antibodies are subsequently identified by screening after each round of selection. The selected monoclonal scFv is cloned into an appropriate vector containing a Fc portion of interest and then produced in mammalian cells to generate an IgG like scFv-Fc fusion protein. - Recombinant Antibody. Recognizes mouse APRIL. Does not recognize mouse BAFF. Species cross-reactivity: Mouse. Clone: Apry-1-3. Isotype: Human IgG1lambda. Applications: ELISA, FUNC (Blocking), IP. Host: Purified from HEK 293 cell culture supernatant. Liquid. In PBS containing 10% glycerol and 0.02% sodium azide. APRIL is a cytokine that belongs to the TNF superfamily and binds to TACI and BCMA. It is implicated in the regulation of tumor cell growth and is involved in monocyte/macrophage-mediated immunological processes. Anti-APRIL (mouse) Monoclonal Antibody (recombinant) (Blocking) (APRY-1-3) is an antibody developed by antibody phage display technology using a human naive antibody gene library. These libraries consist of scFv (single chain fragment variable) composed of VH (variable domain of the human immunoglobulin heavy chain) and VL (variable domain of the human immunoglobulin light chain) connected by a polypeptide linker. The antibody fragments are displayed on the surface of filamentous bacteriophage (M13). This scFv was selected by affinity selection on antigen in a process termed panning. Multiple rounds of panning are performed to enrich for antigen-specific scFv-phage. Monoclonal antibodies are subsequently identified by screening after each round of selection. The selected monoclonal scFv is cloned into an appropriate vector containing a Fc portion of interest and then produced in mammalian cells to generate an IgG like scFv-Fc fusion protein.
  • Reactivity
    Mouse
  • Storage Instruction
    2°C to 8°C,-20°C
  • UNSPSC
    12352203