anti-BAFF (mouse), mAb (blocking) (Sandy-2)

AdipoGen Life Sciences

anti-BAFF (mouse), mAb (blocking) (Sandy-2)

10

ImmunoPrecipitation, Neutralisation/Blocking

Research Use Only

Monoclonal

Sandy-2

1 mg/ml

>95%

Tnfsf13b

tumor necrosis factor (ligand) superfamily, member 13b

b cell-activating factor; BAF; BAFF; BL; BLyS; D8Ertd387; D8Ertd387e; TAL; TALL1; TALL-1; THANK; TNFSF20; Tnlg7a; tumor necrosis factor ligand 7a; tumor necrosis factor ligand superfamily member 13B; zTNF; zTNF4

Mouse

IgG1

BAFF is a master regulator of peripheral B cell survival and, together with IL-6, promotes Ig class-switching and plasma cell differentiation. BAFF co-stimulates activated T cells. Increased levels of soluble BAFF have been detected in the serum of patients with various autoimmune diseases, such as Sjoegrens syndrome, rheumatoid arthritis, multiple sclerosis and systemic lupus erythematosus (SLE). Furthermore, BAFF is found in inflammatory sites in which there is lymphoid neogenesis. BAFF levels are elevated in patients with multiple myeloma and B cell chronic lymphoid leukemia (B-CCL). - Monoclonal Antibody. Recognizes mouse BAFF. Isotype: Mouse IgG1. Clone: Sandy-2. Applications: FUNC (Blocking), IP. Liquid. In PBS containing 10% glycerol and 0.02% sodium azide. BAFF is a master regulator of peripheral B cell survival and, together with IL-6, promotes Ig class-switching and plasma cell differentiation. BAFF co-stimulates activated T cells. Increased levels of soluble BAFF have been detected in the serum of patients with various autoimmune diseases, such as Sjoegrens syndrome, rheumatoid arthritis, multiple sclerosis and systemic lupus erythematosus (SLE). Furthermore, BAFF is found in inflammatory sites in which there is lymphoid neogenesis. BAFF levels are elevated in patients with multiple myeloma and B cell chronic lymphoid leukemia (B-CCL).

Mouse

2°C to 8°C

12352203