anti-BAIAP2 antibody

Arigo Biolaboratories

anti-BAIAP2 antibody

23

Western Blot, ImmunoHistoChemistry, ImmunoHistoChemistry Paraffin

Research Use Only

Polyclonal

0.5 mg/ml

Unconjugated

BAIAP2

BAR/IMD domain containing adaptor protein 2

BAI1 associated protein 2; BAP2; brain-specific angiogenesis inhibitor 1-associated protein 2; fas ligand-associated factor 3; FLAF3; insulin receptor substrate of 53 kDa; insulin receptor substrate p53/p58; insulin receptor substrate protein of 53 kDa; IRS-58; IRSP53; IRSp53/58; WAML; WASP and MIM like

Goat

IgG

The protein encoded by this gene has been identified as a brain-specific angiogenesis inhibitor (BAI1)-binding protein. This adaptor protein links membrane bound G-proteins to cytoplasmic effector proteins. This protein functions as an insulin receptor tyrosine kinase substrate and suggests a role for insulin in the central nervous system. It also associates with a downstream effector of Rho small G proteins, which is associated with the formation of stress fibers and cytokinesis. This protein is involved in lamellipodia and filopodia formation in motile cells and may affect neuronal growth-cone guidance. This protein has also been identified as interacting with the dentatorubral-pallidoluysian atrophy gene, which is associated with an autosomal dominant neurodegenerative disease. Alternative splicing results in multiple transcript variants encoding distinct isoforms.[provided by RefSeq, Jan 2009]

Bovine, Canine, Human

-20°C

12352203