anti-BMPR1B antibody
ARG54831
ApplicationsWestern Blot, ImmunoHistoChemistry, ImmunoHistoChemistry Paraffin
Product group Antibodies
ReactivityChicken, Human, Mouse
TargetBMPR1B
Overview
- SupplierArigo Biolaboratories
- Product Nameanti-BMPR1B antibody
- Delivery Days Customer23
- ApplicationsWestern Blot, ImmunoHistoChemistry, ImmunoHistoChemistry Paraffin
- CertificationResearch Use Only
- ClonalityPolyclonal
- ConjugateUnconjugated
- Gene ID658
- Target nameBMPR1B
- Target descriptionbone morphogenetic protein receptor type 1B
- Target synonymsactivin receptor-like kinase 6; ALK6; ALK-6; AMDD; BDA1D; BDA2; BMP type-1B receptor; BMPR-1B; bone morphogenetic protein receptor type-1B; bone morphogenetic protein receptor, type IB; CDw293; serine/threonine receptor kinase
- HostRabbit
- IsotypeIgG
- Scientific DescriptionThis gene encodes a member of the bone morphogenetic protein (BMP) receptor family of transmembrane serine/threonine kinases. The ligands of this receptor are BMPs, which are members of the TGF-beta superfamily. BMPs are involved in endochondral bone formation and embryogenesis. These proteins transduce their signals through the formation of heteromeric complexes of 2 different types of serine (threonine) kinase receptors: type I receptors of about 50-55 kD and type II receptors of about 70-80 kD. Type II receptors bind ligands in the absence of type I receptors, but they require their respective type I receptors for signaling, whereas type I receptors require their respective type II receptors for ligand binding. Mutations in this gene have been associated with primary pulmonary hypertension. Several transcript variants encoding two different isoforms have been found for this gene. [provided by RefSeq, Feb 2012]
- ReactivityChicken, Human, Mouse
- Storage Instruction-20°C
- UNSPSC12352203