anti-Caspase-1 (p20) (human), mAb (Bally-1) (Biotin)

Catalog number: AG-20B-0048B-C100
Brand: AdipoGen Life Sciences
Packing: 100 ug
Price: € 400.00
Expected delivery time: 7 days

Product specifications for - anti-Caspase-1 (p20) (human), mAb (Bally-1) (Biotin)

Product group: Antibodies
Category: Primary Antibodies
Application: Western Blot
Clonality: Monoclonal
Isotype: IgG1
Source: Purified from concentrated hybridoma tissue culture supernatant.
Purity: >95% (SDS-PAGE)
Datasheet: Datasheet
  Research Use Only
UNSPSC: 12352203
Concentration: 0.5mg/ml
Form supplied: Liquid. In PBS containing 0.02% sodium azide.
Storage instructions: Store at -20°C
Scientific information: 
Scientific info: Caspase-1 is the best-described inflammatory caspase. It processes the cytokines interleukin-1beta (IL-1beta) and IL-18 and induces pyroptotic cell death. Caspase-1 is activated by multiprotein complexes called Inflammasomes in response to numerous stimuli that are detected through distinct inflammasomes. NLRC4 responds to cytosolic flagellin, murine NLRP1b responds to anthrax lethal toxin, AIM2 responds to cytosolic DNA and NLRP3 responds to a variety of agonists including crystals.
Clone ID: Bally-1
Swiss prot ID: P29466
Safety information: 
Additional information: 
Synonyms: AG-20B-0048B-C100; AdipoGen Life Sciences; Interleukin-1 beta Convertase; IL-1BC; Interleukin-1 beta-converting Enzyme; ICE
Liver X receptor beta activation induces pyroptosis of human and murine colon cancer cells: V. Derangere, et al.; Cell Death Differ. 21, 1914 (2014) Read more
Human monocytes engage an alternative inflammasome pathway: M.M. Gaidt, et al.; Immunity 44, 833 (2016) Read more