anti-Caspase-1 (p20) (human), mAb (Bally-1)

Catalog number: AG-20B-0048-C100
Brand: AdipoGen Life Sciences
Packing: 100 ug
Price: € 370.00
Expected delivery time: 7 days
Quantity:

Product specifications for - anti-Caspase-1 (p20) (human), mAb (Bally-1)

Overview: 
Product group: Antibodies
Category: Primary Antibodies
Application: Western Blot
Species: Human
Target: CASP1
Target description: caspase 1
Isotype: IgG1
Source: Purified from concentrated hybridoma tissue culture supernatant.
Properties: 
Purity: >95% (SDS-PAGE)
Datasheet: Datasheet
  Research Use Only
UNSPSC: 12352203
Concentration: 1 mg/ml
Form supplied: Liquid. In PBS containing 10% glycerol and 0.02% sodium azide.
Storage instructions: -20°C
Scientific information: 
Scientific info: Caspase-1 is the best-described inflammatory caspase. It processes the cytokines interleukin-1beta (IL-1beta) and IL-18 and induces pyroptotic cell death. Caspase-1 is activated by multiprotein complexes called Inflammasomes in response to numerous stimuli that are detected through distinct inflammasomes. NLRC4 responds to cytosolic flagellin, murine NLRP1b responds to anthrax lethal toxin, AIM2 responds to cytosolic DNA and NLRP3 responds to a variety of agonists including crystals. - Monoclonal Antibody. Recognizes endogenous full-length and activated (p20 fragment) human caspase-1. Isotype: Mouse IgG1. Clone: Bally-1. Applications: WB. Liquid. In PBS containing 10% glycerol and 0.02% sodium azide. Caspase-1 is the best-described inflammatory caspase. It processes the cytokines interleukin-1beta (IL-1beta) and IL-18 and induces pyroptotic cell death. Caspase-1 is activated by multiprotein complexes called Inflammasomes in response to numerous stimuli that are detected through distinct inflammasomes. NLRC4 responds to cytosolic flagellin, murine NLRP1b responds to anthrax lethal toxin, AIM2 responds to cytosolic DNA and NLRP3 responds to a variety of agonists including crystals.
Clone ID: Bally-1
Gene ID: 834
Swiss prot ID: P29466
Safety information: 
MSDS: MSDS
Additional information: 
Synonyms: CASP1 nirs variant 1; caspase 1, apoptosis-related cysteine peptidase; caspase-1; ICE; IL-1 beta-converting enzyme; IL1BC; IL1B-convertase; interleukin 1, beta, convertase; interleukin 1-B converting enzyme; Interleukin-1 beta convertase; Interleukin-1 beta-converting enzyme; P45
Liver X receptor beta activation induces pyroptosis of human and murine colon cancer cells: V. Derangere, et al.; Cell Death Differ. 21, 1914 (2014) Read more
Human monocytes engage an alternative inflammasome pathway: M.M. Gaidt, et al.; Immunity 44, 833 (2016) Read more