anti-Cathepsin K antibody

Arigo Biolaboratories

anti-Cathepsin K antibody

23

Western Blot

Research Use Only

Polyclonal

0.5 mg/ml

Unconjugated

CTSK

cathepsin K

cathepsin K; cathepsin O; cathepsin O1; cathepsin O2; cathepsin X; CTS02; CTSO; CTSO1; CTSO2; PKND; PYCD

Goat

IgG

The protein encoded by this gene is a lysosomal cysteine proteinase involved in bone remodeling and resorption. This protein, which is a member of the peptidase C1 protein family, is predominantly expressed in osteoclasts. However, the encoded protein is also expressed in a significant fraction of human breast cancers, where it could contribute to tumor invasiveness. Mutations in this gene are the cause of pycnodysostosis, an autosomal recessive disease characterized by osteosclerosis and short stature. This gene may be subject to RNA editing. [provided by RefSeq, Jul 2008]

Bovine, Canine, Human, Mouse, Porcine, Rat

-20°C

12352203