anti-CD137L (human), mAb (41B436)

Catalog number: AG-20A-0031-C050
Brand: AdipoGen Life Sciences
Packing: 50 ug
Other sizes: 100 ug
Price: € 195.00
Expected delivery time: 7 days
Quantity:

Product specifications for - anti-CD137L (human), mAb (41B436)

Overview: 
Product group: Antibodies
Category: Primary Antibodies
Application: ELISA; Flow Cytometry; ImmunoCytoChemistry; Western Blot
Species: Human
Target: TNFSF9
Target description: TNF superfamily member 9
Isotype: IgG1 Kappa
Properties: 
Datasheet: Datasheet
  Research Use Only
UNSPSC: 12352203
Concentration: 1 mg/ml
Form supplied: Liquid. 0.2um-filtered solution in PBS, pH 7.4. Contains no preservatives.
Storage instructions: -20-¦C
Scientific information: 
Scientific info: Monoclonal Antibody. Recognizes extracellular domain of human CD137L. Does not cross-react with mouse CD137L. Isotype: Mouse IgG1kappa. Clone: 41B436. Applications: ELISA, FACS, ICC, WB. Liquid. 0.2microm-filtered solution in PBS, pH 7.4. Contains no preservatives. The CD137 ligand (CD137L, 4-1BBL) is a member of the tumor necrosis factor (TNF) family. CD137L is a type II, transmembrane protein found on activated macrophages, dendritic cells and mature B cells. The interaction with its receptor 4-1BB induces recruitment of TNF receptor-associated factor 1 (TRAF1) and TRAF2 and interaction with the kinase p56lck. CD137 and CD137L have been reported to be involved in tumor rejection, apoptosis, anti-viral immunity, diabetes, in T and B cell co-stimulation and modulation of the immune response. - The CD137 ligand (CD137L, 4-1BBL) is a member of the tumor necrosis factor (TNF) family. CD137L is a type II, transmembrane protein found on activated macrophages, dendritic cells and mature B cells. The interaction with its receptor 4-1BB induces recruitment of TNF receptor-associated factor 1 (TRAF1) and TRAF2 and interaction with the kinase p56lck. CD137 and CD137L have been reported to be involved in tumor rejection, apoptosis, anti-viral immunity, diabetes, in T and B cell co-stimulation and modulation of the immune response.
Clone ID: 41B436
Gene ID: 8744
Swiss prot ID: P41273
Safety information: 
MSDS: MSDS
Additional information: 
Synonyms: 4-1BB ligand; 4-1BBL; 4-1BB-L; CD137L; homolog of mouse 4-1BB-L; receptor 4-1BB ligand; TNLG5A; tumor necrosis factor (ligand) superfamily, member 9; tumor necrosis factor ligand 5A; tumor necrosis factor ligand superfamily member 9; tumor necrosis factor superfamily member 9
Inhibition of proliferation and induction of apoptosis in multiple myeloma cell lines by CD137 ligand signaling: C. Gullo, et al.; PLoS One. 5, e10845 (2010) Read more
Tumor necrosis factor receptor 1 associates with CD137 ligand and mediates its reverse signaling: M.C. Moh, et al.; FASEB J. 27, 2957 (2013) Read more
Expression of CD137 on Hodgkin and Reed-Sternberg cells inhibits T-cell activation by eliminating CD137 ligand expression: W.T. Ho, et al.; Cancer Res. 73, 652 (2013) Read more