anti-CD137L (human), mAb (41B436)

Catalog number: AG-20A-0031-C100
Brand: AdipoGen Life Sciences
Packing: 100 ug
Other sizes: 50 ug
Price: € 270.00
Expected delivery time: 7 days

Product specifications for - anti-CD137L (human), mAb (41B436)

Product group: Antibodies
Category: Primary Antibodies
Application: ELISA, FACS, ImmunoCytoChemistry, Western Blot
Clonality: Monoclonal
Isotype: IgG1 Kappa
Datasheet: Datasheet
  Research Use Only
UNSPSC: 12352203
Concentration: 1mg/ml
Form supplied: Liquid. 0.2um-filtered solution in PBS, pH 7.4. Contains no preservatives.
Storage instructions: Store at -20°C
Scientific information: 
Scientific info: The CD137 ligand (CD137L, 4-1BBL) is a member of the tumor necrosis factor (TNF) family. CD137L is a type II, transmembrane protein found on activated macrophages, dendritic cells and mature B cells. The interaction with its receptor 4-1BB induces recruitment of TNF receptor-associated factor 1 (TRAF1) and TRAF2 and interaction with the kinase p56lck. CD137 and CD137L have been reported to be involved in tumor rejection, apoptosis, anti-viral immunity, diabetes, in T and B cell co-stimulation and modulation of the immune response.
Clone ID: 41B436
Swiss prot ID: P41273
Safety information: 
Additional information: 
Synonyms: AG-20A-0031-C100; AdipoGen Life Sciences; 4-1BBL; TNFSF9
Inhibition of proliferation and induction of apoptosis in multiple myeloma cell lines by CD137 ligand signaling: C. Gullo, et al.; PLoS One. 5, e10845 (2010) Read more
Tumor necrosis factor receptor 1 associates with CD137 ligand and mediates its reverse signaling: M.C. Moh, et al.; FASEB J. 27, 2957 (2013) Read more
Expression of CD137 on Hodgkin and Reed-Sternberg cells inhibits T-cell activation by eliminating CD137 ligand expression: W.T. Ho, et al.; Cancer Res. 73, 652 (2013) Read more