anti-CD14 antibody [MEM-18] (low endotoxin)
ARG65491
ApplicationsFunctional Assay, Flow Cytometry, ImmunoPrecipitation, Western Blot, ELISA
Product group Antibodies
ReactivityHuman
TargetCD14
Overview
- SupplierArigo Biolaboratories
- Product Nameanti-CD14 antibody [MEM-18] (low endotoxin)
- Delivery Days Customer23
- ApplicationsFunctional Assay, Flow Cytometry, ImmunoPrecipitation, Western Blot, ELISA
- CertificationResearch Use Only
- ClonalityMonoclonal
- Clone IDMEM-18
- Concentration1 mg/ml
- ConjugateUnconjugated
- Estimated Purity>95%
- Gene ID929
- Target nameCD14
- Target descriptionCD14 molecule
- Target synonymsmonocyte differentiation antigen CD14; myeloid cell-specific leucine-rich glycoprotein
- HostMouse
- IsotypeIgG1
- Scientific DescriptionCD14 is a 55 kDa GPI-anchored glycoprotein, constitutively expressed on the surface of mature monocytes, macrophages, and neutrophils, where serves as a multifunctional lipopolysaccharide receptor; it is also released to the serum both as a secreted and enzymatically cleaved GPI-anchored form. CD14 binds lipopolysaccharide molecule in a reaction catalyzed by lipopolysaccharide-binding protein (LBP), an acute phase serum protein. The soluble sCD14 is able to discriminate slight structural differences between lipopolysaccharides and is important for neutralization of serum allochthonous lipopolysaccharides by reconstituted lipoprotein particles. CD14 affects allergic, inflammatory and infectious processes.
- ReactivityHuman
- Storage Instruction-20°C
- UNSPSC12352203