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anti-CD155 (PVR) (human), mAb (ANC6A3) (R-PE)

Research Use Only
ANC-350-050
Ancell Corporation
ApplicationsFlow Cytometry, ELISA
Product group Antibodies
ReactivityHuman
Price on request
Packing Size
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Overview

  • Supplier
    Ancell Corporation
  • Product Name
    anti-CD155 (PVR) (human), mAb (ANC6A3) (R-PE)
  • Delivery Days Customer
    10
  • Applications
    Flow Cytometry, ELISA
  • Certification
    Research Use Only
  • Clonality
    Monoclonal
  • Clone ID
    ANC6A3
  • Concentration
    0.5 mg/ml
  • Conjugate
    RPE
  • Estimated Purity
    >95%
  • Host
    Mouse
  • Isotype
    IgG1
  • Scientific Description
    Human CD155 (Polio Virus Receptor, PVR, Necl-5) is a 70 kd type I Ig superfamily molecule. It is involved in formation of intracellular junctions between epithelial cells. Its ligands include CD226 (DNAM-1), and CD96 (TACTILE). CD155 expression by tumor has been shown to be upregulated by nitric oxide. A soluble version of CD155 has been shown to exist. High CD155 expression has recently been exploited to use engineered poliovirus to treat glioblastoma. - Monoclonal antibody. Binds to cell surface CD155 on U-937 cells and to recombinant CD155 in ELISA assay. The antibody clones ANC6A3 and ANC2B2 (#ANC-255-020) bind to distict epitopes of CD155 and are suitable as a matched pair for a sandwich ELISA assay. Applications: ELISA, FACS. Isotype: Mouse IgG1kappa. Clone: ANC6A3. 50mM Sodium Phosphate pH 7.5, 500mM Potassium Chloride, 150mM NaCl, 15% Glycerol, 0.2% BSA, 0.04% NaN3 (as a preservative). Human CD155 (Polio Virus Receptor, PVR, Necl-5) is a 70 kd type I Ig superfamily molecule. It is involved in formation of intracellular junctions between epithelial cells. Its ligands include CD226 (DNAM-1), and CD96 (TACTILE). CD155 expression by tumor has been shown to be upregulated by nitric oxide. A soluble version of CD155 has been shown to exist. High CD155 expression has recently been exploited to use engineered poliovirus to treat glioblastoma.
  • Reactivity
    Human
  • Storage Instruction
    2°C to 8°C
  • UNSPSC
    12352203