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anti-CD16 antibody [LNK16] (FITC)

Research Use Only
ARG62744
Arigo Biolaboratories
ApplicationsFlow Cytometry
Product group Antibodies
ReactivityHuman
TargetFCGR3A
Price on request
Packing Size
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Overview

  • Supplier
    Arigo Biolaboratories
  • Product Name
    anti-CD16 antibody [LNK16] (FITC)
  • Delivery Days Customer
    23
  • Applications
    Flow Cytometry
  • Certification
    Research Use Only
  • Clonality
    Monoclonal
  • Clone ID
    LNK16
  • Conjugate
    FITC
  • Gene ID2214
  • Target name
    FCGR3A
  • Target description
    Fc fragment of IgG receptor IIIa
  • Target synonyms
    CD16; CD16A; CD16a antigen; Fc fragment of IgG, low affinity III, receptor for (CD16); Fc fragment of IgG, low affinity IIIa, receptor (CD16a); Fc gamma receptor III-A; FCG3; Fc-gamma receptor III-2 (CD 16); Fc-gamma receptor IIIb (CD16); Fc-gamma RIII-alpha; FcgammaRIIIA; FCGR3; FCGRIII; FCR-10; FCRIII; FCRIIIA; IGFR3; igG Fc receptor III-2; IMD20; immunoglobulin G Fc receptor III; low affinity immunoglobulin gamma Fc region receptor III-A; low affinity immunoglobulin gamma receptor III-a Fc fragment; neutrophil-specific antigen NA
  • Host
    Mouse
  • Isotype
    IgG1
  • Scientific Description
    CD16 (FcgammaRIII) is a 50-65 kDa glycoprotein serving as a low affinity IgG receptor. Human FcgammaRIII is expressed in two forms - FcgammaRIII-A and -B. FcgammaRIII-A is a transmembrane protein of monocytes, macrophages, NK cells and a subset of T cells. It is associated with FcepsilonRI-gamma subunit and is responsible for antibody-dependent NK cell cytotoxicity. Mast cell FcgammaRIII-A is associated, moreover, with FcepsilonRI-beta subunit. Besides IgG, FcgammaRIII-A can be triggered also by oligomeric IgE. FcgammaRIII-B is a GPI-linked monomeric receptor expressed on neutrophils and is involved in their activation and induction of a proadhesive phenotype.
  • Reactivity
    Human
  • Storage Instruction
    2°C to 8°C
  • UNSPSC
    12352203