anti-CD160 antibody [BY55] (PE)

Arigo Biolaboratories

anti-CD160 antibody [BY55] (PE)

23

Flow Cytometry

Research Use Only

Monoclonal

BY55

RPE

CD160

CD160 molecule

BY55; CD160 antigen; CD160-delta Ig; natural killer cell receptor BY55; natural killer cell receptor, immunoglobulin superfamily member; NK1; NK28

Mouse

IgM

CD160 is a cell surface glycoprotein of immunoglobulin superfamily, which functions as a costimulatory receptor expressed mainly on cytotoxic cell populations and recognizing both classical and non-classical MHC class I molecules. It can form disulfide-linked multimers. Down-modulation of CD160 occurs as a consequence of its proteolytic cleavage and the released soluble form was found to impair the MHC-class I specific cytotoxicity of CD8+ T lymphocytes and NK cells. In contrast to GPI-anchored isoform with broader expression among CD160 positive cells, expression of the transmembrane isoform is restricted to NK cells and is activation-dependent.

Human

2°C to 8°C

12352203