anti-CD178 / Fas Ligand antibody [NOK-1] (PE)

Arigo Biolaboratories

anti-CD178 / Fas Ligand antibody [NOK-1] (PE)

23

Flow Cytometry

Research Use Only

Monoclonal

NOK-1

RPE

FASLG

Fas ligand

ALPS1B; apoptosis (APO-1) antigen ligand 1; apoptosis antigen ligand; APT1LG1; APTL; CD178; CD95 ligand; CD95L; CD95-L; fas antigen ligand; Fas ligand (TNF superfamily, member 6); FASL; mutant tumor necrosis factor family member 6; TNFSF6; TNLG1A; tumor necrosis factor ligand 1A; tumor necrosis factor ligand superfamily member 6

Mouse

IgG1

CD178 / Fas-L (Fas ligand, CD95L), a member of TNF family transmembrane glycoproteins, is responsible for induction of apoptosis in cells containing its receptor CD95 / Fas. The CD178-mediated apoptosis pathway has been implicated in peripheral tolerance, tissue pathology, and maintenance of the immune privileged sites. Defects in this interaction may be related to some cases of systemic lupus erythematosus (SLE). CD178 was also described as a co-stimulatory receptor for T-cell activation in mice in vivo.

Human

2°C to 8°C

12352203