anti-CD26 / DPP4 antibody [BA5b]
ARG62788
ApplicationsFlow Cytometry, Other Application
Product group Antibodies
ReactivityHuman
TargetDPP4
Overview
- SupplierArigo Biolaboratories
- Product Nameanti-CD26 / DPP4 antibody [BA5b]
- Delivery Days Customer23
- ApplicationsFlow Cytometry, Other Application
- CertificationResearch Use Only
- ClonalityMonoclonal
- Clone IDBA5b
- Concentration1 mg/ml
- ConjugateUnconjugated
- Estimated Purity>95%
- Gene ID1803
- Target nameDPP4
- Target descriptiondipeptidyl peptidase 4
- Target synonymsADABP; ADCP2; ADCP-2; adenosine deaminase complexing protein 2; CD26; dipeptidyl peptidase 4; dipeptidyl peptidase IV; dipeptidylpeptidase 4; dipeptidylpeptidase IV (CD26, adenosine deaminase complexing protein 2); DPP IV; DPPIV; Gly-Pro naphthylamidase; Post-proline dipeptidyl aminopeptidase IV; T-cell activation antigen CD26; TP103; Xaa-Pro-dipeptidylaminopeptidase
- HostMouse
- IsotypeIgG2a
- Scientific DescriptionCD26, also known as dipeptidyl peptidase IV (DPP-IV), is a homodimeric cell surface serine peptidase that degradates IFN-gamma-induced cytokines, acts as a T cell costimulatory molecule, and participates in multiple immunopathological roles in leukocyte homing and inflammation. Alterations in its peptidase activity are characteristic of malignant transformation. The enzymatic activity increases dramatically with tumour grade and severity. CD26 is expressed in various blood cell types, but also e.g. in cells that are histogenetically related to activated fibroblasts. Alterations in CD26 density have been reported on circulating monocytes and CD4+ T cells during rheumatoid arthritis and systemic lupus erythematosus.
- ReactivityHuman
- Storage Instruction-20°C
- UNSPSC12352203