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anti-CD266 / TWEAK R antibody [ITEM-4] (low endotoxin)

Research Use Only
ARG65467
Arigo Biolaboratories
ApplicationsFunctional Assay, Flow Cytometry, Western Blot, ImmunoHistoChemistry, ImmunoHistoChemistry Frozen
Product group Antibodies
ReactivityHuman
TargetTNFRSF12A
Price on request
Packing Size
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Overview

  • Supplier
    Arigo Biolaboratories
  • Product Name
    anti-CD266 / TWEAK R antibody [ITEM-4] (low endotoxin)
  • Delivery Days Customer
    23
  • Applications
    Functional Assay, Flow Cytometry, Western Blot, ImmunoHistoChemistry, ImmunoHistoChemistry Frozen
  • Certification
    Research Use Only
  • Clonality
    Monoclonal
  • Clone ID
    ITEM-4
  • Concentration
    1 mg/ml
  • Conjugate
    Unconjugated
  • Estimated Purity
    >95%
  • Gene ID51330
  • Target name
    TNFRSF12A
  • Target description
    TNF receptor superfamily member 12A
  • Target synonyms
    CD266; FGF-inducible 14; fibroblast growth factor-inducible immediate-early response protein 14; FN14; tumor necrosis factor receptor superfamily member 12A; TWEAKR; tweak-receptor; type I transmembrane protein Fn14
  • Host
    Mouse
  • Isotype
    IgG2b
  • Scientific Description
    CD266 / TWEAK R (TNFRSF12A), also known as FN14 (fibroblast growth factor-inducible 14) is a receptor for CD255 / TWEAK, the TNF-like weak inducer of apoptosis. CD266 is expressed on endothelial cells, as well as on some cancer tissues, and plays a role in CD255-induced endothelial cell migration, proliferation, and angiogenesis. The CD255-CD266 interaction, or antibody-mediated triggering of CD266 is also able to induce apoptosis and necrosis in CD266-positive cells (including tumor cells), which might have therapeutic potential.
  • Reactivity
    Human
  • Storage Instruction
    -20°C
  • UNSPSC
    12352203