anti-CD272 [BTLA] (human), mAb (ANC6E9)

Catalog number: ANC-272-020
Brand: Ancell Corporation
Packing: 100 ug
Price: € 195.00
Expected delivery time: 7 days
Quantity:

Product specifications for - anti-CD272 [BTLA] (human), mAb (ANC6E9)

Overview: 
Product group: Antibodies
Category: Primary Antibodies
Application: ELISA, FACS, FUNC (Blocking)
Clonality: Monoclonal
Isotype: IgG1 Kappa
Properties: 
Datasheet: Datasheet
  Research Use Only
UNSPSC: 12352203
Form supplied: 50 mM Sodium Phosphate pH 7.5, 100 mM Potassium Chloride, 150mM NaCl, 0.5% Gentamicin sulfate
Storage instructions: Store at +4°C
Scientific information: 
Scientific info: Human CD272 (BTLA, B and T Lymphocyte Attenuator) is a member of the immunoglobulin superfamily and has sequence homology to PD-1 and CTLA-4. It is expressed on T and B lymphocytes and other hemopoetic lineages. Engagement of this molecule by its ligand CD270 (HVEM) can downregulate activated T and B cell responses. CD272 levels on antigen specific CD8+ T cells have been reported to decrease in viral specific, but not melanoma specific activated lines. Polymorphism of the CD272 molecule has been linked to rheumatoid arthritis.
Clone ID: ANC6E9
Additional information: 
Synonyms: ANC-272-020; Ancell Corporation; BTLA; B- and T-lymphocyte Attenuator