anti-CD273 [B7-DC/PD-L2] (human), mAb (ANC8D12)

Ancell Corporation

anti-CD273 [B7-DC/PD-L2] (human), mAb (ANC8D12)

10

Flow Cytometry, ELISA, Neutralisation/Blocking

Research Use Only

Monoclonal

ANC8D12

>95%

Mouse

IgG2a

CD273 (B7-DC; PD-L2) is a type I surface molecule with homology to CD80, CD86, CD274. It is expressed primarily by dendritic cells and provides a stimulatory signal to CD279 (PD-1; Programmed Cell Death 1) which has an important immunoregulatory role by downregulating the T cell response. CD273 binds to CD279 (PD-1) with a 2-6 fold higher affinity than CD274 and is an important component of immune regulation. - Monoclonal Antibody. Isotype: Mouse IgG2akappa. Clone: ANC8D12. Applications: ELISA, FACS, FUNC (Blocking). 50mM Sodium Phosphate pH 7.5, 100mM Potassium Chloride, 150mM NaCl, 0.5% Gentamicin sulfate. CD273 (B7-DC; PD-L2) is a type I surface molecule with homology to CD80, CD86, CD274. It is expressed primarily by dendritic cells and provides a stimulatory signal to CD279 (PD-1; Programmed Cell Death 1) which has an important immunoregulatory role by downregulating the T cell response. CD273 binds to CD279 (PD-1) with a 2-6 fold higher affinity than CD274 and is an important component of immune regulation.

Human

2°C to 8°C

12352203