anti-CD273 [B7-DC/PD-L2] (human), mAb (ANC8D12)

Catalog number: ANC-273-020
Brand: Ancell Corporation
Packing: 100 ug
Price: € 195.00
Expected delivery time: 7 days

Product specifications for - anti-CD273 [B7-DC/PD-L2] (human), mAb (ANC8D12)

Product group: Antibodies
Category: Primary Antibodies
Application: ELISA, FACS, FUNC (Blocking)
Clonality: Monoclonal
Isotype: IgG2a Kappa
Purity: >95% (SDS-PAGE)
Datasheet: Datasheet
  Research Use Only
UNSPSC: 12352203
Form supplied: 50mM Sodium Phosphate pH 7.5, 100mM Potassium Chloride, 150mM NaCl, 0.5% Gentamicin sulfate.
Storage instructions: Store at +4°C
Scientific information: 
Scientific info: CD273 (B7-DC, PD-L2) is a type I surface molecule with homology to CD80, CD86, CD274. It is expressed primarily by dendritic cells and provides a stimulatory signal to CD279 (PD-1, Programmed Cell Death 1) which has an important immunoregulatory role by downregulating the T cell response. CD273 binds to CD279 (PD-1) with a 2-6 fold higher affinity than CD274 and is an important component of immune regulation.
Clone ID: ANC8D12
Additional information: 
Synonyms: ANC-273-020; Ancell Corporation; CD273 / PD-L2; PDCD1LG2; bA574F11.2; PDL2; PDCD1L2; PD-L2; CD273; Btdc; B7DC; programmed death ligand 2; butyrophilin B7-DC; PDCD1 ligand 2; PD-1-ligand 2; PD-1 ligand 2; B7-DC; B7 dendritic cell molecule; programmed cell death 1 ligand 2