anti-CD274 [B7-H1/PD-L1] (human), mAb (ANC6H1)

Catalog number: ANC-274-020
Brand: Ancell Corporation
Packing: 100 ug
Price: € 195.00
Expected delivery time: 7 days

Product specifications for - anti-CD274 [B7-H1/PD-L1] (human), mAb (ANC6H1)

Product group: Antibodies
Category: Primary Antibodies
Application: ELISA, FACS
Clonality: Monoclonal
Isotype: IgG1 Kappa
Datasheet: Datasheet
  Research Use Only
UNSPSC: 12352203
Form supplied: 50 mM Sodium Phosphate pH 7.5, 100 mM Potassium Chloride, 150mM NaCl, 0.5% Gentamicin sulfate
Storage instructions: Store at +4°C
Scientific information: 
Scientific info: CD274 (B7-H1, PD-L1, Programmed Death Ligand) is a member of the B7 family and is expressed on a variety of tissues including lymphoid cells. It plays an important role in regulation of T cell activation and is involved in progression of cancer, arthritis and HIV infection. CD274 binding to its receptor CD279 (PD-1) on activated T cells can decrease proliferation. Conversely, ligation of CD279 on primed T cells can stimulate IL-10 production. High levels of CD274 present in renal cell carcinoma is associated with poor prognosis. Tumor expressed CD274 can increase apoptosis of tumor specific T cells resulting in better tumor cell survival.
Clone ID: ANC6H1
Additional information: 
Synonyms: ANC-274-020; Ancell Corporation; B7-H1; Programmed Cell Death 1 Ligand 1; PD-L1; PDCD1 Ligand 1 B7-H1 / PD-L1 / CD274; CD274; PDL1; PDCD1LG1; PDCD1L1; B7H1; B7-H; CD274 antigen; B7 homolog CD274 molecule