anti-CD275 [B7-H2] (human), mAb (ANC4E3)

Catalog number: ANC-263-020
Brand: Ancell Corporation
Packing: 100 ug
Price: € 195.00
Expected delivery time: 7 days

Product specifications for - anti-CD275 [B7-H2] (human), mAb (ANC4E3)

Product group: Antibodies
Category: Primary Antibodies
Application: ELISA
Clonality: Monoclonal
Isotype: IgG1 Kappa
Datasheet: Datasheet
  Research Use Only
UNSPSC: 12352203
Form supplied: 50 mM Sodium Phosphate pH 7.5, 100 mM Potassium Chloride, 150mM NaCl, 0.5% Gentamicin sulfate
Storage instructions: Store at +4°C
Scientific information: 
Scientific info: The inducible costimulator CD278 (ICOS) is similar to human CD28 (24% homology) and plays an analogous role in the T cell activation process. Signaling through CD278 is particularly important in progression of TH2 immune response. The receptor for human CD278 (ICOS) is CD275 (GL50), a member of the B7 family sharing 20% homology with CD80 (B7-1) and CD86 (B7-2). Blockade of the CD278-CD275 interaction in mice improves allograft survival and reduces EAE.
Clone ID: ANC4E3
Additional information: 
Synonyms: ANC-263-020; Ancell Corporation; ICOSL / B7-H2; ICOSLG; LICOS; ICOSL; ICOS-L; GL50; CD275; B7RP1; B7RP-1; B7H2; B7-H2; transmembrane protein B7-H2 ICOS ligand; ICOS ligand; B7-related protein 1; B7-like protein Gl50; B7 homologue 2; B7 homolog 2; inducible T-cell co-stimulator ligand