anti-CD278 [ICOS] (human), mAb (ANC6C6) (APC)

Ancell Corporation

anti-CD278 [ICOS] (human), mAb (ANC6C6) (APC)

10

Functional Assay, Flow Cytometry, ELISA

Research Use Only

Monoclonal

ANC6C6

APC

Mouse

IgG1

Monoclonal Antibody. Isotype: Mouse IgG1kappa. Clone: ANC6C6. Applications: ELISA, FACS, FUNC. 50 mM Sodium Phosphate pH 7.5, 500 mM Potassium Chloride, 150mM NaCl, 15% Glycerol, 0.2% BSA, 0.04% NaN3 (as a preservative). The inducible costimulator CD278 (ICOS) is similar to human CD28 (24% homology) and plays an analogous role in the T cell activation process. Secondary signaling through CD28 or CD278 results in discrete cytokine secretion profiles by the activated T cells. CD275 (ICOSL; GL50; B7-H2) has been shown to be the ligand for CD278 (ICOS). - The inducible costimulator CD278 (ICOS) is similar to human CD28 (24% homology) and plays an analogous role in the T cell activation process. Secondary signaling through CD28 or CD278 results in discrete cytokine secretion profiles by the activated T cells. CD275 (ICOSL; GL50; B7-H2) has been shown to be the ligand for CD278 (ICOS).

Human

2°C to 8°C

12352203