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anti-CD3 epsilon antibody [145-2C11] (APC)

Research Use Only
ARG62808
Arigo Biolaboratories
ApplicationsFlow Cytometry, Western Blot, ImmunoHistoChemistry, Neutralisation/Blocking, Other Application
Product group Antibodies
ReactivityMouse
TargetCd3e
Price on request
Packing Size
Large volume orders?
Order with a bulk request

Overview

  • Supplier
    Arigo Biolaboratories
  • Product Name
    anti-CD3 epsilon antibody [145-2C11] (APC)
  • Delivery Days Customer
    23
  • Applications
    Flow Cytometry, Western Blot, ImmunoHistoChemistry, Neutralisation/Blocking, Other Application
  • Certification
    Research Use Only
  • Clonality
    Monoclonal
  • Clone ID
    145-2c11
  • Concentration
    0.1 mg/ml
  • Conjugate
    APC
  • Gene ID12501
  • Target name
    Cd3e
  • Target description
    CD3 antigen, epsilon polypeptide
  • Target synonyms
    AI504783; CD3; CD3epsilon; T3e; T-cell surface antigen T3/Leu-4 epsilon chain; T-cell surface glycoprotein CD3 epsilon chain
  • Host
    Hamster
  • Isotype
    IgG1
  • Scientific Description
    CD3 subunit complex is crucial in transducing antigen-recognition signals into the cytoplasm of T cells and in regulating the cell surface expression of the TCR complex. T cell activation through the antigen receptor (TCR) involves the cytoplasmic tails of the CD3 subunits CD3 gamma, CD3 delta, CD3 epsilon and CD3 zeta. These CD3 subunits are structurally related members of the immunoglobulins superfamily encoded by closely linked genes on human chromosome 11. The CD3 components have long cytoplasmic tails that associate with cytoplasmic signal transduction molecules. This association is mediated at least in part by a double tyrosine-based motif present in a single copy in the CD3 subunits. CD3 may play a role in TCR-induced growth arrest, cell survival and proliferation.
  • Reactivity
    Mouse
  • Storage Instruction
    2°C to 8°C
  • UNSPSC
    12352203