anti-CD3 antibody [CT-3] (Biotin)

Arigo Biolaboratories

anti-CD3 antibody [CT-3] (Biotin)

23

Flow Cytometry, ImmunoHistoChemistry, ImmunoHistoChemistry Frozen, ImmunoHistoChemistry Paraffin

Research Use Only

Monoclonal

CT-3

0.5 mg/ml

Biotin

CD3D

CD3d molecule

CD3; CD3 glycoprotein; CD3 type I transmembrane glycoprotein; CD3D antigen delta; CD3D antigen, delta polypeptide (TiT3 complex); CD3d molecule, delta (CD3-TCR complex); T-cell surface glycoprotein CD3 delta chain; T-cell surface protein

Mouse

IgG1

The protein encoded by this gene is part of the T-cell receptor/CD3 complex (TCR/CD3 complex) and is involved in T-cell development and signal transduction. The encoded membrane protein represents the delta subunit of the CD3 complex, and along with four other CD3 subunits, binds either TCR alpha/beta or TCR gamma/delta to form the TCR/CD3 complex on the surface of T-cells. Defects in this gene are a cause of severe combined immunodeficiency autosomal recessive T-cell-negative/B-cell-positive/NK-cell-positive (SCIDBNK). Two transcript variants encoding different isoforms have been found for this gene. Other variants may also exist, but the full-length natures of their transcripts has yet to be defined. [provided by RefSeq, Feb 2009]

Chicken

2°C to 8°C

12352203