anti-CD40 (human), mAb (EA-5)

Catalog number: ANC-300-020
Brand: Ancell Corporation
Packing: 100 ug
Price: € 158.00
Expected delivery time: 7 days
Quantity:

Product specifications for - anti-CD40 (human), mAb (EA-5)

Overview: 
Product group: Antibodies
Category: Primary Antibodies
Application: ELISA, FACS, FUNC
Clonality: Monoclonal
Isotype: IgG1
Properties: 
Datasheet: Datasheet
  Research Use Only
UNSPSC: 12352203
Form supplied: 50 mM Sodium Phosphate pH 7.5, 100 mM Potassium Chloride, 150mM NaCl, 0.5% Gentamicin sulfate
Storage instructions: Store at +4°C
Scientific information: 
Scientific info: CD40 belongs to the TNF-receptor superfamily and is essential in mediating a broad variety of immune and inflammatory responses including T cell-dependent immunoglobulin class switching, memory B cell development and germinal center formation. The interaction of CD40-CD40L is necessary for amyloid-beta-induced microglial activation, and thus is thought to be an early event in Alzheimer disease pathogenesis. CD40 is constitutively expressed by antigen presenting cells, including dendritic cells, B cells and macrophages. Consistent with its widespread expression on normal cells, CD40 is also expressed on a wide range of tumor cells, including non-Hodgkin's and Hodgkin's lymphomas, myeloma and some carcinomas including nasopharynx, bladder, cervix, kidney and ovary.
Clone ID: EA-5
Additional information: 
Synonyms: ANC-300-020; Ancell Corporation; CD40L Receptor; CDw40; Tumor Necrosis Factor Receptor Superfamily Member 5; TNFRSF5