anti-CD58 antibody [MEM-63] (FITC)

Arigo Biolaboratories

anti-CD58 antibody [MEM-63] (FITC)

23

Flow Cytometry

Research Use Only

Monoclonal

MEM-63

FITC

CD58

CD58 molecule

ag3; CD58 antigen, (lymphocyte function-associated antigen 3); LFA3; LFA-3; lymphocyte function-associated antigen 3; surface glycoprotein LFA-3

Mouse

IgG1

CD58 (LFA-3) is an immunoglobulin family adhession molecule expressed by both hematopoietic and non-hematopoietic cells (often on antigen presenting cells) and serving as ligand of CD2. This interaction is important for T cell-mediated immunity. CD58 is expressed in transmembrane form and in GPI-anchored form; the later is constitutively associated with protein kinases whereas the transmembrane form activates kinase activity upon triggering. CD58 is a powerful tool for detection of minimal residual disease in acute lymphocytic leukemia, and for evaluation of liver damage related with hepatitis B.

Human

2°C to 8°C

12352203