anti-CD8 antibody [YCATE55.9]

Arigo Biolaboratories

anti-CD8 antibody [YCATE55.9]

23

Flow Cytometry, ImmunoFluorescence, ImmunoCytoChemistry, ImmunoHistoChemistry, ImmunoHistoChemistry Frozen

Research Use Only

Monoclonal

YCATE55.9

1 mg/ml

Unconjugated

CD8A

CD8a molecule

CD8 antigen, alpha polypeptide (p32); T-cell surface glycoprotein CD8 alpha chain

Rat

IgG1

CD8 antigen is a cell surface glycoprotein found on most cytotoxic T lymphocytes that mediates efficient cell-cell interactions within the immune system. The CD8 antigen acts as a coreceptor with the T-cell receptor on the T lymphocyte to recognize antigens displayed by an antigen presenting cell in the context of class I MHC molecules. The coreceptor functions as either a homodimer composed of two alpha chains or as a heterodimer composed of one alpha and one beta chain. Both alpha and beta chains share significant homology to immunoglobulin variable light chains. This gene encodes the CD8 alpha chain. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Nov 2011]

Canine

-20°C

12352203